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Reducing Implant-Related Infection with Bioactive Glass

Post Time:Mar 13,2019Classify:Industry NewsView:931

Bioactive glass is a type of glass made from high-purity chemicals, such as silica, calcium, and boron, which induce specific biological activity. Bioactive glass, by virtue of its high strength, low weight and biocompatibility, has been widely used in a range of biomedical applications, including tissue engineering, bone grafting, dental reconstruction and wound healing.

Such clinical experience has shown that borate bioactive glass possesses antimicrobial properties against a wide range of bacteria, including MRSA and E-coli.6,7 The antimicrobial efficacy is achieved through an increase in pH of the surrounding body fluids (which is stressful for bacteria) and because any bacteria that do approach are unable to adhere to bioactive glass and so cannot create microfilms on its surface.8,9 In vitro studies have confirmed that bioactive glass has strong anti-staphylococcal and anti-streptococcal activity.10,11

Since the antimicrobial action of bioactive glass arises from it creating an environment that is hostile to bacteria rather than requiring direct contact with the invading microbe in order to kill it, it is effective across a wide range of bacteria. Furthermore, the bacteria cannot adapt to such effects, and so no bacteria have been found to develop resistance to the antimicrobial effects of bioactive glass

Mo-Sci Health Care has extensive experience in the manufacture of bioactive glasses. Bioactive glasses have the ability to bond to soft and/or hard tissue and are biodegradable in the body. The release of ions and the formation of hydroxyapatite supports the regeneration of bone tissue and can accelerate the healing process.


Source: glassonline.comAuthor: Shangyi

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